What is Cell Revival?

CELL REVIVAL combines the synergistic effects of the next generation anti-aging supplement NIAGEN® Nicotinamide Riboside (NR), the unique ingredient composition of MOBILEE® for increased joint mobility¹ and enhanced muscle strength² and 5 complementing ingredients - Biotin, Vitamin A, C, D and E. Cell Revival supports the body’s daily joint and mobility function through its special formulation.

  1. Why Cell Revival? 
    1. Cell Revival’s anti-aging ingredients are backed by science
    2. Cell Revival has natural Ingredients and is certified safe and effective
    3. Cell Revival is convenient and cost effective
  2. How does Cell Revival work?
    1. Role of NAD in our body
    2. How NR help increase NAD?
    3. Role of Hyaluronic acid, Collagen and Glycosaminoglycans (GAGs) in the body
    4. Role of Mobilee
  3. Product Benefits
  4. Ingredients
  5. Suitable For
  6. Recommended Dosage
  7. Caution
  8. Related Scientific Studies

Why Cell Revival?


Cell Revival’s anti-aging ingredients are backed by science.

CELL REVIVAL’s patented key ingredients, NIAGEN® and MOBILEE® are supported by clinical studies. NIAGEN® Nicotinamide Riboside (NR) has four published human studies supporting healthy aging and has more than 150 scientific articles published since its discovery in 2004. Among the many studies are the pre-clinical studies on the administration of Nicotinamide Riboside (NR) which was shown to restore muscle mass by preserving NAD levels³ and prevent muscle weakness by improving cell mitochondrial function⁴.

Cell Revival has natural Ingredients and is certified safe and effective.

NIAGEN® NR is found naturally in trace amounts in cow’s milk, whey protein, and brewer’s yeast. It is a combination of niacinamide and ribose and is a more potent, no-flush version of Niacin (Vitamin B3). NIAGEN® is the world’s first and only known FDA-safety reviewed form of NR. It’s been demonstrated in more than four clinical trials to safely and effectively increase NAD in humans. NIAGEN® is manufactured in the U.S. under cGMP (current Good Manufacturing Practice) regulations enforced by the FDA. NIAGEN® is manufactured in the U.S. by ChomaDex under cGMP (current Good Manufacturing Practice) regulations enforced by the FDA. Niagen is certified vegetarian, gluten-free, nut-free, caffeine-free and has no animal byproducts, no artificial colors or flavors

Mobilee® is a patented natural ingredient extracted from rooster comb with a unique composition that is particularly rich in hyaluronic acid, polysaccharides and collagen. Mobilee® has been authorized as a Novel Food by the European Food Safety Authority (EFSA) and has received GRAS status in the USA. Mobilee® is the result of years of research conducted by Bioibérica, a leading joint-health biotechnology company.

Cell Revival is convenient and cost effective.

Cell Revival combines two potent ingredients plus supporting nutrients which could be taken in one capsule with synergistic effects on cellular health, mobility, joint and muscle health. Moreover, oral intake of Mobilee® which is rich in hyaluronic acid, can be a convenient alternative to taking the injectable form in addressing joint pain.



How Does Cell Revival Work?


Role of NAD in our body

To appreciate how NR works, we need to understand the critical role of NAD in the aging process of our bodies.  Nicotinamide Adenine Dinucleotide is a co-enzyme which plays a vital role in energy production to help the body perform every day functions such as breathing, eating, sleeping, etc. Another major role of NAD is to boost the longevity-promoting proteins called sirtuins⁷⁻¹². More recently, NAD has been identified also as a major player in skeletal muscle development, regeneration, aging, and disease¹³. Research shows that as we age levels of NAD decline substantially. With less NAD, it is harder for the cells in our body to stay healthy as we age.

How NR help increase NAD?

For NAD to perform its role, it needs a precursor or a catalyst to aid in its formation. Nicotinamide Riboside (NR) acts as a natural precursor to NAD production. While there are other possible precursors, NR is deemed most effective in performing its role in NAD production and help boost sirtuin without the skin flush issue.

Role of Hyaluronic acid, Collagen and Glycosaminoglycans (GAGs) in the body

Hyaluronic acid (HA) is a substance that is naturally present in the human body. It is found in the highest concentrations in fluids in the eyes and joints. A key function of hyaluronic acid is to help lubricate joints, skin, and the eyes. However, as the body ages, HA levels decrease. HA provides lubrication to the connective tissues of our joints. It also has an important part of our skin’s overall health. Collagen on the other hand, is an abundant protein found in bones, muscles, skin and tendons. It provides skin with structure and strengthen the bones. Similarly, Collagen also is depleted as the body grows older. Glycosaminoglycans (GAGs) are complex polysaccharides with important role in in maintaining structural integrity of most tissues, particularly connective tissues by forming hydrated matrices and interacting with collagen¹⁴

Role of Mobilee

The synergistic effect of the ingredients of Mobilee® hyaluronic acid (HA,) collagen and glycosaminoglycans (GAGs) helps improve HA level, reduce joint discomfort and increase muscle strength . In addition, combined effect also is demonstrated to enhance skin and joint health⁵⁻⁷.



Product Benefits


Support on Cellular Health

Clinically demonstrated to significantly increase NAD+*
Promotes mitochondria health*
Promotes healthy cellular metabolism*
Promotes healthy aging*
Improves muscle quality and strength*
Helps boost memory and combat Alzheimer’s*
Counters the effects of high-fat diet*

Support on Joint and Muscle Health

10-fold increase of the endogenous synthesis of hyaluronic acid in joints*
Reduction of inflammation by lowering Prostaglandin E2*
Reduction of clinical synovial effusion and joint discomfort*
Increase of muscle strength*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


Ingredients


NIAGEN®Nicotinamide Riboside (NR) is the world’s first and only known FDA-safety reviewed form of NR, a unique next-generation vitamin B3 family. It has been demonstrated in more than four clinical trials to safely and effectively increase Nicotinamide Adenine Dinucleotide or NAD levels in humans. NAD is a co-enzyme which plays a vital role in energy production to help the body perform every day functions such as breathing, eating, sleeping, etc. Another major role of NAD is to boost the longevity-promoting proteins called sirtuins ⁷⁻¹². 

Mobilee® is a patented natural ingredient with a unique composition that is rich in hyaluronic acid, polysaccharides and collagen. Mobilee®  has been proven to reduce joint discomfort through increased endogenous hyaluronic acid (HA) secretion by 10-fold⁵ and reduced inflammation of the joints⁶.

Biotin (Vitamin B7) assists in energy production.

Vitamin A (Beta carotene) helps maintain a strong heart, immune function, and eye and lung health.

Vitamin C (Ascorbic acid) fights cancer cells (antioxidant) and helps in collagen production to keep skin healthy.

Vitamin D (Cholecalciferon) supports calcium absorption for healthy bone density.

Vitamin E (D-alpha tocopherol) helps defend cells against oxidative stress caused by sunlight, pollution, and stress.



Suitable For


  • People with joint problems
  • People with work-related musculoskeletal disorders
  • Athletes
  • People with aging concerns
  • People with sleeping problems
  • People with imbalanced diet


Recommended Dosage

  • 2 capsules per day with a glass of water in the morning before breakfast
  • 60 capsules per bottle, providing consumption for 30 days


Caution

Keep out of the reach of children. This product is for adult use only. When taking any dietary supplement, please consult a doctor or a qualified healthcare professional, before using. It is not intended for use by children, pregnant women, or nursing mothers.

Related Scientific Studies


¹ Sanchez et al (2013)– Ann Nutr Metab 63 (suppl. 1): 538

² Martínez-Puig et al (2013) Mediterr J Nutr Metab. 6:63-68

³ Frederick DW. Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle. Cell Metab. 2016 Aug 9;24(2):269-82.  https://www.ncbi.nlm.nih.gov/pubmed/27508874

⁴ Sarika Srivastava Emerging therapeutic roles for NAD+ metabolism in mitochondrial and age-related disorders. Clin Transl Med. 2016; 5: 25  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963347/

⁵ Khan NA et al. Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3.  EMBO Mol Med.2014 Jun;6(6):721-31. doi: 10.1002/emmm.201403943. https://www.ncbi.nlm.nih.gov/pubmed/24711540

⁶ Torrent et al (2009) Osteoarthritis and Cartilage. 17(1): S277-278

⁷ Torrent et al (2010) Osteoarthritis and Cartilage. 18(2): S246-247.

⁸ Imai, S. and L. Guarente, NAD+ and sirtuins in aging and disease. Trends Cell Biol, 2014. 24(8): p. 464-71.

⁹ Boutant, M. and C. Canto, SIRT1 metabolic actions: Integrating recent advances from mouse models. Mol Metab, 2014. 3(1): p. 5-18.

¹⁰ Mouchiroud, L., et al., The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling. Cell, 2013. 154(2): p. 430-41.

¹¹ Kanfi, Y., et al., The sirtuin SIRT6 regulates lifespan in male mice. Nature, 2012. 483(7388): p. 218-21.

¹² Chang, H.C. and L. Guarente, SIRT1 and other sirtuins in metabolism. Trends Endocrinol Metab, 2014. 25(3): p. 138-45.

¹³ Michelle F et al. A need for NAD+ in muscle development, homeostasis, and aging. Published online 2018 Mar 7. https://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30350-3

¹⁴ Vascular Medicine: A Companion to Braunwald's Heart Disease (Second Edition), 2013 https://www.sciencedirect.com/science/article/pii/B9781437729306000045